李直-广州医科大学卫生管理学院

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南山学者

李直

教授

研究方向

精神疾病的脑、遗传与环境机制

电子邮箱

lizhi@gzhmu.edu.cn

个人简介

李直，中国科学院大学认知神经科学博士，广州医科大学应用心理学系教授，博士生导师，广州医科大学“南山学者”骨干人才，英国剑桥大学精神病学系访问学者，美国约翰·霍普金斯大学医学院博士后。研究领域包括利用行为遗传学、多模态脑影像学（磁共振、脑磁图、脑电图）、基因组学和环境组学等技术研究精神分裂症与抑郁症的大脑、遗传和环境机制。

学历背景

2007.9-2012.6，广州医科大学应用心理学，获理学学士学位
2013.9-2018.6，中国科学院大学认知神经科学，获理学博士学位

工作经历

2018.10-2023.7，Lieber Institute for Brain Development博士后
2023.7至今，广州医科大学

主要研究成果

1.Li, Z., Huang, J., Hung, K. S. Y., Deng, Y., Wang, Y., Wang, Y., Lui, S. S. Y., Mak, H. K. F., Sham, P. C., Cheung, E. F. C., Öngür, D., Dazzan, P., & Chan, R. C. K. (2021). Cerebellar hypoactivation is associated with impaired sensory integration in schizophrenia. Journal of Abnormal Psychology, 130(1), 102–111.
2.Li, Z., Yan, H., Zhang, X., Shah, S., Yang, G., Chen, Q., Han, S., Zhang, D., Weinberger, D. R., Yue, W., & Tan, H. Y. (2021). Air pollution interacts with genetic risk to influence cortical networks implicated in depression. Proceedings of the National Academy of Sciences of the United States of America, 118(46). doi:10.1073/pnas.2109310118
3.Li, Z., Wang, Y., Yan, C., Cheung, E. F. C., Docherty, A. R., Sham, P. C., Gur, R. E., Gur, R. C., & Chan, R. C. K. (2019). Inheritance of Neural Substrates for Motivation and Pleasure. Psychological Science, 30(8), 1205-1217. doi:10.1177/0956797619859340.
4.Li, Z., Huang, J., Xu, T., Wang, Y., Li, K., Zeng, Y. W., Lui, S. S. Y., Cheung, E. F. C., Jin, Z., Dazzan, P., Glahn, D. C., & Chan, R. C. K. (2018). Neural mechanism and heritability of complex motor sequence and audiovisual integration: A healthy twin study. Human Brain Mapping, 39(3), 1438-1448. doi:10.1002/hbm.23935.
5.Li, Z., Shi, H. S., Elis, O., Yang, Z. Y., Wang, Y., Lui, S. S. Y., Cheung, E. F. C., Kring, A. M., & Chan, R. C. K. (2018). The structural invariance of the Temporal Experience of Pleasure Scale across time and culture. PsyCh Journal, 7(2), 59-67. doi:10.1002/pchj.207.
6.Li, Z., Zhang, C. Y., Huang, J., Wang, Y., Yan, C., Li, K., Zeng, Y. W., Jin, Z., Cheung, E. F. C., Su, L., & Chan, R. C. K. (2018). Improving motivation through real-time fMRI-based self-regulation of the nucleus accumbens. Neuropsychology, 32(6), 764-776. doi:10.1037/neu0000425.
7.Li, Z., Yan, C., Lv, Q.-y., Yi, Z.-h., Zhang, J.-y., Wang, J.-h., Lui, S. S. Y., Xu, Y.-f., Cheung, E. F. C., Gur, R. E., Gur, R. C., & Chan, R. C. K. (2017). Striatal dysfunction in patients with schizophrenia and their unaffected first-degree relatives. Schizophrenia Research. doi:https://doi.org/10.1016/j.schres.2017.08.043.
8.Li, Z., Shi, Y. F., Parker, G. J., Huang, J., Yan, C., Lui, S. S. Y., Cheung, E. F. C., Neumann, D. L., Shum, D. H. K., & Chan, R. C. K. (2016). Devaluation of Rewards for the Future Is Associated With Schizotypal Personality Features. Australian Psychologist, 51(6), 481-489. doi:10.1111/ap.12141.
9.Xu, T., Wang, Y., Li, Z., Huang, J., Lui, S. S., Tan, S. P., Yu, X., Cheung, E. F., He, M. G., Ott, J., Gur, R. E., Gur, R. C., & Chan, R. C. K. (2016). Heritability and familiality of neurological soft signs: evidence from healthy twins, patients with schizophrenia and non-psychotic first-degree relatives. Psychological Medicine, 46(1), 117-123. doi:10.1017/S0033291715001580.
10.Li, Z., Lui, S. S., Geng, F. L., Li, Y., Li, W. X., Wang, C. Y., Tan, S. P., Cheung, E. F., Kring, A. M., & Chan, R. C. K. (2015). Experiential pleasure deficits in different stages of schizophrenia. Schizophrenia Research, 166(1-3), 98-103. doi:10.1016/j.schres.2015.05.041.
11.Li, Z., Yan, C., Xie, W. Z., Li, K., Zeng, Y. W., Jin, Z., Cheung, E. F., & Chan, R. C. K. (2015). Anticipatory pleasure predicts effective connectivity in the mesolimbic system. Frontiers in Behavioral Neuroscience, 9, 217. doi:10.3389/fnbeh.2015.00217.

科研项目

职称	教授	职务
邮箱	lizhi@gzhmu.edu.cn	分管工作
研究方向	精神疾病的脑、遗传与环境机制	学历背景	2007.9-2012.6，广州医科大学应用心理学，获理学学士学位 2013.9-2018.6，中国科学院大学认知神经科学，获理学博士学位
工作经历	2018.10-2023.7，Lieber Institute for Brain Development博士后 2023.7至今，广州医科大学	主要研究成果	1.Li, Z., Huang, J., Hung, K. S. Y., Deng, Y., Wang, Y., Wang, Y., Lui, S. S. Y., Mak, H. K. F., Sham, P. C., Cheung, E. F. C., Öngür, D., Dazzan, P., & Chan, R. C. K. (2021). Cerebellar hypoactivation is associated with impaired sensory integration in schizophrenia. Journal of Abnormal Psychology, 130(1), 102–111. 2.Li, Z., Yan, H., Zhang, X., Shah, S., Yang, G., Chen, Q., Han, S., Zhang, D., Weinberger, D. R., Yue, W., & Tan, H. Y. (2021). Air pollution interacts with genetic risk to influence cortical networks implicated in depression. Proceedings of the National Academy of Sciences of the United States of America, 118(46). doi:10.1073/pnas.2109310118 3.Li, Z., Wang, Y., Yan, C., Cheung, E. F. C., Docherty, A. R., Sham, P. C., Gur, R. E., Gur, R. C., & Chan, R. C. K. (2019). Inheritance of Neural Substrates for Motivation and Pleasure. Psychological Science, 30(8), 1205-1217. doi:10.1177/0956797619859340. 4.Li, Z., Huang, J., Xu, T., Wang, Y., Li, K., Zeng, Y. W., Lui, S. S. Y., Cheung, E. F. C., Jin, Z., Dazzan, P., Glahn, D. C., & Chan, R. C. K. (2018). Neural mechanism and heritability of complex motor sequence and audiovisual integration: A healthy twin study. Human Brain Mapping, 39(3), 1438-1448. doi:10.1002/hbm.23935. 5.Li, Z., Shi, H. S., Elis, O., Yang, Z. Y., Wang, Y., Lui, S. S. Y., Cheung, E. F. C., Kring, A. M., & Chan, R. C. K. (2018). The structural invariance of the Temporal Experience of Pleasure Scale across time and culture. PsyCh Journal, 7(2), 59-67. doi:10.1002/pchj.207. 6.Li, Z., Zhang, C. Y., Huang, J., Wang, Y., Yan, C., Li, K., Zeng, Y. W., Jin, Z., Cheung, E. F. C., Su, L., & Chan, R. C. K. (2018). Improving motivation through real-time fMRI-based self-regulation of the nucleus accumbens. Neuropsychology, 32(6), 764-776. doi:10.1037/neu0000425. 7.Li, Z., Yan, C., Lv, Q.-y., Yi, Z.-h., Zhang, J.-y., Wang, J.-h., Lui, S. S. Y., Xu, Y.-f., Cheung, E. F. C., Gur, R. E., Gur, R. C., & Chan, R. C. K. (2017). Striatal dysfunction in patients with schizophrenia and their unaffected first-degree relatives. Schizophrenia Research. doi:https://doi.org/10.1016/j.schres.2017.08.043. 8.Li, Z., Shi, Y. F., Parker, G. J., Huang, J., Yan, C., Lui, S. S. Y., Cheung, E. F. C., Neumann, D. L., Shum, D. H. K., & Chan, R. C. K. (2016). Devaluation of Rewards for the Future Is Associated With Schizotypal Personality Features. Australian Psychologist, 51(6), 481-489. doi:10.1111/ap.12141. 9.Xu, T., Wang, Y., Li, Z., Huang, J., Lui, S. S., Tan, S. P., Yu, X., Cheung, E. F., He, M. G., Ott, J., Gur, R. E., Gur, R. C., & Chan, R. C. K. (2016). Heritability and familiality of neurological soft signs: evidence from healthy twins, patients with schizophrenia and non-psychotic first-degree relatives. Psychological Medicine, 46(1), 117-123. doi:10.1017/S0033291715001580. 10.Li, Z., Lui, S. S., Geng, F. L., Li, Y., Li, W. X., Wang, C. Y., Tan, S. P., Cheung, E. F., Kring, A. M., & Chan, R. C. K. (2015). Experiential pleasure deficits in different stages of schizophrenia. Schizophrenia Research, 166(1-3), 98-103. doi:10.1016/j.schres.2015.05.041. 11.Li, Z., Yan, C., Xie, W. Z., Li, K., Zeng, Y. W., Jin, Z., Cheung, E. F., & Chan, R. C. K. (2015). Anticipatory pleasure predicts effective connectivity in the mesolimbic system. Frontiers in Behavioral Neuroscience, 9, 217. doi:10.3389/fnbeh.2015.00217.
科研项目